The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of the patient’s blood. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets. Think of Selphyl® PRFM as the next generation PRP. Once the PRP is injected, it triggers the growth and migration of healthy, new skin cells as well as encouraging growth of a stronger collagen structure – increasing facial firmness and lift.


Selphyl® PRFM is utilized by physicians in their practices for various applications. The process is simple and the entire procedure takes approximately 30 minutes. While it may be possible to achieve your desired results after just one treatment, additional treatments are generally recommended. Your doctor will determine the best approach for you individually.

The Power of Platelets

Platelets and other components in human blood migrate to a site of injury. Platelets are known to release a variety of growth factors that respond to tissue injury, where they initiate and promote healing. By concentrating platelets at the site of injury, physicians have the potential to enhance the body’s natural capacity for healing which leaves a fantastic glow to your skin.

Microneedling facial with PRFM

Once the PRP is converted into PRFM, the PRFM solution is then applied to the client’s face and is used as the primary serum throughout a microneedling facial with the Rejuvapen®. Microneedling with PRFM creates micro channels in the skin. This enhances accumulation of collagen and elastin which helps tighten and thicken the skin leaving a healthy afterglow.  

PRFM Injectables

For Face: When PRFM is injected, the growth factor found in platelets stimulates the skin cells, which lead to an increase in collagen, an essential factor for firm and elastic skin. Since this method uses regenerative power of your own platelets to remove wrinkles, you will experience a more natural looking result. PRFM, as mentioned above, revitalizes the skin itself, so you will benefit from its effects much longer.

Benefits of PRFM injections for hair restoration:

  1. Treatment takes only about 30 minutes.
  2. Injections are well-tolerated by most patients. (we offer PRONOX™ for your comfort)
  3. Side effects are minor and temporary.
  4. Since we use a substance extracted from your own blood, there is no risk of allergic reaction.
  5. With a series of PRFM injection sessions, noticeable change occurs within several weeks.
  6. Initial PRFM hair treatment cost is generally comparable to or less costly than laser therapy.

Our practice is one of the only practices in the area that offers ProNox™. This state-of-the-art system delivers patients a mixture of 50% oxygen and 50% nitrous oxide. Also known as laughing gas, ProNox is a patient-administered system that helps to relieve pain and anxiety during a variety of medical procedures, including the aesthetic procedures offered at Dr. Sierra’s practice. Best of all, it begins working almost immediately, and there’s no downtime after you stop treatment! It is safe and goes away quickly enough for you to drive yourself home after your procedure. (*Does not apply to all procedures).